SAM-e, Double Strength (Disulfate Tosylate), 400 mg, 60 Enteric Coated Tablets

Science-Based Nutrition™Helps Support Mood and Neural FunctionHelps Support Joint Comfort and MobilityHelps Support Liver Health and DetoxificationVegetarianDietary SupplementNon-GMO / Gluten Free / Soy FreeFormulated with Disulfate TosylateDoctor's Best utilizes only the highest quality Italian Soloesse® SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse® SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.Supplementing with SAM-eSoloesse® Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body.SAM-e and Mood and Cognitive FunctionSAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.SAM-e and Joint FunctionIn clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.SAM-e and Liver FunctionSAM-e helps support healthy levels of glutathione, a critical anti-oxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.Double Strength SAM-e is sealed in blister packs for freshness and stability.

SAMe (Disulfate Tosylate), 400 mg, 60 Enteric Coated Caplets

NutraLife™ Health Products Incorporated400 mg Active S-Adenosyl-Methionine Per TabletManufactured in Accordance with GMPDietary SupplementNutraLife™ SAMe™ Enteric Coated Tablets are Kosher Certified by Star-KClinically Shown To Maintain:Mood & amp; Emotional Well BeingHealthy Liver FunctionJoint Health and ComfortJoint MobilitySAMe is found in every living being. It is an important physiological agent synthesized by the body, and it is involved in over 40 biochemical reactions, some of which effect:MOOD SAMe and Emotional Well Being:SAMe is essential to the manufacture of many important brain compounds such as neurotransmitters and phospholipids, which are critical for maintaining healthy mood and emotional well-being.JOINTS SAMe and Joint Mobility:Clinical studies indicate that SAMe may play an important role in the manufacture of cartilage and that SAMe helps produce proteoglycans, essential components in healthy joint and mobility.LIVER SAMe and Liver Function:SAMe is involved in many processes of the liver. SAMe is essential to maintaining glutathione levels, which is critical for proper liver function.As people age, SAMe levels can decrease. SAMe supplementation may be an important factor in maintaining mobility, and a healthy body and mind.NutraLife SAMe:NutraLife SAMe is the same form that has been available in Europe for over two decades. NutraLife offers the only form of SAMe with 20 years of historical data for both effectiveness and safety. NutraLife SAMe is manufactured and packaged with the highest quality and safety standards.Each NutraLife SAMe tablet contains 400 mg of active S-Adenosyl-Methionine and is manufactured in full accordance with GMP.NutraLife SAMe is the original SAMe brand introduced to the United States almost a decade ago.NutraLife SAMe continues to be made with the highest quality active S,S isomer SAMe raw material.NutraLife SAMe is kosher certified by Star-K and contains NO animal byproducts.NutraLife SAMe does not contain Talc.NutraLife SAMe tablets are manufactured in a carefully controlled environment and are cold form blister packed to ensure a more than two year stability rating.NutraLife™ SAMe™ tablets are sealed in blister packs to ensure product safety, quality and freshness.

SAMe (Disulfate Tosylate), 200 mg, 60 Enteric Coated Tablets

S-adenosyl-L-methionineSupports Joint Comfort, Function and MobilityEnteric Coated TabletsDietary SupplementSource Naturals® SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients.Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage.The studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier, where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules. Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication.SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. However, levels of SAMe tend to decline with age.

SAMe ( Disulfate Tosylate), 400 mg, 60 Enteric Coated Tablets

Lake Avenue Nutrition SAMe (S-Adenosyl L-Methionine) & nbsp;Featuring SAMe from S-Adenosyl L-Methionine Disulfate TosylateSuitable for VegetariansEnteric-Coated TabletsSupports Joint, Mood, and Liver Health* & nbsp;Formulated without GMOs, Gluten, or SoyProduced in a GMP FacilityLake Avenue Nutrition & nbsp;SAMe delivers an important compound, known as S-adenosyl L-methionine directly to the body. This compound is necessary for proper functions within the body and can support joint, mood, and liver health.*Benefits of SAMeThis important compound assists the body in producing a wide range of other compounds that support many different functions. It can help the body produce neurotransmitters, like serotonin and dopamine that help regulate mood.* It can also help the body produce cartilage compounds such as glycosaminoglycans to support joint health.* Though SAMe is a naturally-occurring compound, sometimes our bodies do not produce enough, requiring additional intake through a supplement.Lake Avenue Nutrition SAMe contains S-adenosyl L-methionine sourced from S-adenosyl-L-methionine disulfate tosylate. It delivers this compound in enteric-coated tablets for easy supplementation into your diet.

SAMe (Disulfate Tosylate), 400 mg, 60 Enteric Coated Tablets

Nervous System SupportSupports Emotional Well-BeingSupports Joint HealthEnteric CoatedNew Oval TabletEnteric CoatedA Dietary SupplementVegetarian/VeganKosherAmino AcidsFamily Owned Since 1968GMP Quality AssuredSAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient minor aches and pains resulting from overexertion or strain. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW® SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.

SAMe (Disulfate Tosylate), 200 mg, 60 Enteric Coated Tablets

200 mg Active S-Adenosyl-Methionine Per TabletManufactured in Accordance with GMPDietary SupplementNutraLife SAMe™ Enteric Coated Tablets are Kosher Certified By: Star KosherClinically Shown To Maintain:Mood & amp; Emotional Well BeingHealthy Liver FunctionJoint Health and ComfortJoint MobilitySAMe is found in every living being. It is an important physiological agent synthesized by the body, and it is involved in over 40 biochemical reactions, some of which affect:MOOD SAMe and Emotional Well Being:SAMe is essential to the manufacture of many important brain compounds such as neurotransmitters and phospholipids, which are critical for maintaining healthy mood and emotional well-being.JOINTS SAMe and Joint Mobility:Clinical studies indicate that SAMe may play an important role in the manufacture of cartilage and that SAMe helps produce proteoglycans, essential components in healthy joint and mobility.LIVER SAMe and Liver Function:SAMe is involved in many processes of the liver. SAMe is essential to maintaining glutathione levels, which is critical for proper liver function.As people age, SAMe levels can decrease. SAMe supplementation may be an important factor in maintaining mobility, and a healthy body and mind.NutraLife SAMe:NutraLife SAMe is the same form that has been available in Europe for over two decades. NutraLife offers the only form of SAMe with 20 years of historical data for both effectiveness and safety. NutraLife SAMe is manufactured and packaged with the highest quality and safety standards.Each NutraLife SAMe tablet contains 200 mg of active S-Adenosyl-Methionine and is manufactured in full accordance with GMP.NutraLife SAMe is the original SAMe brand introduced to the United States almost a decade ago.NutraLife SAMe continues to be made with the highest quality active S,S isomer SAMe raw material.NutraLife SAMe is kosher certified by Star-K and contains no animal byproducts.NutraLife SAMe does not contain Talc.NutraLife SAMe tablets are manufactured in a carefully controlled environment and are cold form blister packed to ensure a more than two year stability rating.

SAMe (Disulfate Tosylate), 200 mg, 60 Enteric Coated Tablets

Science-Based Nutrition™Helps Support Mood and Neural FunctionHelps Support Joint Comfort and MobilityHelps Support Liver Health and DetoxificationDietary SupplementVegetarian™Non-GMO / Gluten Free / Soy FreeFormulated with Disulfate TosylateDoctor's Best utilizes only the highest quality Italian Soloesse® SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our SAM-e 200 contains 200 mg of active Soloesse SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.Supplementing with SAM-eSoloesse® Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate biochemical activity in the human body.SAM-e and Mood and Cognitive FunctionSAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.SAM-e and Joint FunctionIn clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.SAM-e and Liver FunctionSAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidyl-choline and L-cysteine, both necessary for maintaining liver health.

SAMe (Disulfate Tosylate), 200 mg, 120 Veg Capsules

Nervous System Support Stabilized SAMe, Capsule Form No Enteric Coating Needed Supports Joint Health Non-GMO A Dietary Supplement Vegetarian/Vegan Amino Acids Family Owned Since 1968 GMP Quality Assured SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism.

SAMe (Disulfate Tosylate), 400 mg, 30 Enteric Coated Tablets

Full PotencyIn Foil Blister PackNaturalpH SensitiveFood GradeEnteroGuard® CoatingS-Adenosyl Methionine400 mg (Net Yield) SAM-e from 800 mg SAM-e tosylate DisulfateHighest Concentration of Active S,S FormEnteric-Coated TabletsNet Yield: 400 Mg SAM-eGluten FreeVeganDietary SupplementPromotes:Joint StrengthLiver DetoxificationMood and Brain FunctionJarrow Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.Contains More of the Active S,S FormFound in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) & nbsp; SAM-e, the highest active level available.SAM-e has been clinically shown to have the following benefits:Joint StrengthSAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-E metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.Brain MetabolismSAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).LiverSAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

SAMe (Disulfate Tosylate), 400 mg, 60 Enteric Coated Tablets

In Foil Blister PackpH SensitiveFood GradeEnteroGuard® CoatingS-Adenosyl Methionine400 mg (Net Yield) SAM-e from 800 SAM-e Tosylate DisulfateHighest Concentration of Active S,S FormEnteric-Coated TabletsGluten FreeVeganDietary SupplementSupports:Joint StrengthBrain Metabolism and MoodLiver FunctionJarrow Formulas® SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.Contains More of the Active S,S FormFound in all living cells, SAM-e is a metabolite of methionine (and essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) & nbsp;SAM-e, the highest active level available.SAM-e supportsJoint HealthSAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-E metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.Brain Metabolism and MoodSAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes and precursor to acetylcholine, as well as neurotransmitters such as dopamine, norepinephrine, and serotonin, and has been shown to have a positive effect on mood.Liver FunctionSAMe metabolism supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

SAMe (Disulfate Tosylate), 200 mg, 30 Slow Release Tablets

Dietary SupplementMood & amp; Joint SupportSuitable for Vegetarians/VegansSAMe supports mood and has a positive effect on emotional well-being. It also maintains joint health. Natural Factors SAMe is released slowly. & nbsp;Isura®: & nbsp;Non-GMO: ✔DocumentationMass Spec: ✔Lab Tested

SAMe (Disulfate Tosylate), 400 mg, 30 Enteric Coated Tablets

Double Strength400 mg Active S-Adenosyl-Methionine Per TabletManufactured in Accordance with GMPDietary SupplementNutraLife SAMe Enteric Coated Tablets are Kosher Certified by Star KosherClinically Shown To Maintain:Mood & amp; Emotional Well BeingHealthy Liver FunctionJoint Health and ComfortJoint MobilitySAMe is found in every living being. It is an important physiological agent synthesized by the body, and it is involved in over 40 biochemical reactions, some of which effect:MOOD SAMe and Emotional Well Being:SAMe is essential to the manufacture of many important brain compounds such as neurotransmitters and phospholipids, which are critical for maintaining healthy mood and emotional well-being.JOINTS SAMe and Joint Mobility:Clinical studies indicate that SAMe may play an important role in the manufacture of cartilage and that SAMe helps produce proteoglycans, essential components in healthy joint function and mobility.LIVER SAMe and Liver Function:SAMe is involved in many processes of the liver. SAMe is essential to maintaining glutathione levels, which is critical for proper liver function.As people age, SAMe levels can decrease. SAMe supplementation may be an important factor in maintaining mobility, and a healthy body and mind.NutraLife SAMe:NutraLife SAMe is the same form that has been available in Europe for over two decades. NutraLife offers SAMe with over 40 years of historical data for both effectiveness and safety. NutraLife SAMe is manufactured and packaged with the highest quality and safety standards.Each NutraLife SAMe tablet contains 400 mg of active S-Adenosyl-Methionine and is manufactured in full accordance with GMP.NutraLife SAMe is the original SAMe brand introduced to the United States over three decade ago.NutraLife SAMe continues to be made with the highest quality active S,S isomer SAMe raw material.NutraLife SAMe is kosher certified by Star-K and contains NO animal byproducts.NutraLife SAMe does not contain Talc.NutraLife SAMe tablets are manufactured in a carefully controlled environment and are cold form blister packed to ensure a more than two year stability rating.NutraLife SAMe tablets are sealed in blister packs to ensure product safety, quality and freshness.

SAMe 200, 200 mg, 60 Tablets

Full PotencyIn Foil Blister PackpH SensitiveFood GradeEnteroGuard® CoatingS-Adenosyl Methionine200 mg (Net Yield) SAM-e from 400 mg SAM-e tosylate DisulfateHighest Concentration of Active S,S FormEnteric-Coated TabletsNet Yield -200 Mg SAM-eGluten FreeVeganDietary SupplementSupports:Joint StrengthBrain Metabolism and MoodLiver FunctionJarrow Formulas® SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.Contains More of the Active S,S FormFound in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) & nbsp;SAM-e, the highest active level available.SAMe supports:Joint StrengthSAME supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGS, such as glucosamine sulfate and chondroitin sulfate.Brain MetabolismSAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes and precursor to acetylcholine, as well as neurotransmitters such as dopamine, norepinephrine, and serotonin, and has been shown to have a positive effect on mood.LiverSAMe metabolism supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

SAMe (Disulfate Tosylate), 200 mg, 60 Veg Capsules

Nervous System Support Stabilized SAMe, Capsule Form No Enteric Coating Needed Supports Joint Health Non-GMO A Dietary Supplement Vegetarian/Vegan Amino Acids Family Owned Since 1968 GMP Quality AssuredSAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism.

SAMe (Disulfate Tosylate), 200 mg, 60 Slow Release Tablets

Dietary SupplementMood & amp; Joint SupportSuitable for Vegetarians/VegansSAMe supports mood and has a positive effect on emotional well-being. It also maintains joint health. Natural Factors SAMe is released slowly.Isura®: & nbsp;Non-GMO: Documentation ✔Mass Spec: Lab Tested ✔

Double Strength SAM-e (Disulfate Tosylate), 400 mg, 30 Enteric Coated Tablets

Double-StrengthScience-Based Nutrition™Helps Supports Mood and Neural FunctionHelps Supports Joint Comfort and MobilityHelps Supports Liver Health and DetoxificationVegetarian™Dietary SupplementNon-GMO / Gluten Free / Soy FreeFormulated with Disulfate TosylateDoctor's Best utilizes only the highest quality Italian Soloesse® SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse® SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood.* SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.Supplementing with SAM-eSoloesse® Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body.SAM-e and Mood and Cognitive FunctionSAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.SAM-e and Joint FunctionIn clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.SAM-e and Liver FunctionSAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

SAMe (Disulfate Tosylate), 200 mg, 20 Enteric Coated Tablets

pH SensitiveFood GradeEnteroGuard® CoatingIn Foil Blister PackNaturalFull Potency200 mg (Net Yield) SAMe from 400 mg SAMe Tosylate DisulfateHighest Concentration of Active S,S FormGluten FreeVeganDietary SupplementSuitable for Vegetarians/VegansPromotes:Joint StrengthLiver DetoxificationMood and Brain FunctionJarrow Formulas® SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.Contains More of the Active S,S FormFound in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule and consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) & nbsp;SAMe, the highest active level available.SAMe has been clinically shown to have the following benefits:Joint StrengthSAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.Brain MetabolismSAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).LiverSAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.